› 3l8c

X-ray diffraction
2.41Å resolution

Structure of probable D-alanine--poly(phosphoribitol) ligase subunit-1 from Streptococcus pyogenes

Released:
DOI: 10.2210/pdb3l8c/pdb
PDB entry 3l8c coloured by chain, front view.
PDB entry 3l8c coloured by chain, side view.
PDB entry 3l8c coloured by chain, top view.
Source organism: Streptococcus pyogenes serotype M6
Entry authors: Ramagopal UA, Toro R, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
(1a) ATP + D-alanine = (D-alanyl)adenylate + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178496 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-alanine--D-alanyl carrier protein ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 521 amino acids
Theoretical weight: 58.14 KDa
Source organism: Streptococcus pyogenes serotype M6
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5XBN5 (Residues: 3-512; Coverage: 100%)
Gene names: M6_Spy1043, dltA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21212
Unit cell:
a: 89.024Å b: 153.736Å c: 84.794Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.217 0.275
Expression system: Escherichia coli BL21(DE3)

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