› 3l92

X-ray diffraction
1.89Å resolution

Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.

Released:
DOI: 10.2210/pdb3l92/pdb
PDB entry 3l92 coloured by chain, front view.
PDB entry 3l92 coloured by chain, side view.
PDB entry 3l92 coloured by chain, top view.
Source organism: Yersinia pestis CO92
Entry authors: Osipiuk J, Maltseva N, Makowska-grzyska M, Kwon K, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo hexamer
homo trimer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187215 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphopantetheine adenylyltransferase Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 17.95 KDa
Source organism: Yersinia pestis CO92
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8ZJN9 (Residues: 1-159; Coverage: 100%)
Gene names: YPO0053, YP_0054, coaD, kdtB, y0088
Sequence domains: Cytidylyltransferase-like
Structure domains: HUPs

Ligands and Environments

1 bound ligand:
Ligand COA 1 x COA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R32
Unit cell:
a: 114.82Å b: 114.82Å c: 119.074Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.164 0.192
Expression system: Escherichia coli BL21(DE3)

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