› 3ldv

X-ray diffraction
1.77Å resolution

1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961

Released:
DOI: 10.2210/pdb3ldv/pdb
PDB entry 3ldv coloured by chain, front view.
PDB entry 3ldv coloured by chain, side view.
PDB entry 3ldv coloured by chain, top view.
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Entry authors: Halavaty AS, Shuvalova L, Minasov G, Dubrovska I, Winsor J, Glass EM, Peterson SN, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
Orotidine 5'-phosphate = UMP + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192045 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Orotidine 5'-phosphate decarboxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 255 amino acids
Theoretical weight: 27.78 KDa
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KQT7 (Residues: 1-231; Coverage: 100%)
Gene names: VC_1911, pyrF
Sequence domains: Orotidine 5'-phosphate decarboxylase / HUMPS family
Structure domains: Aldolase class I

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand CL 4 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 47.3Å b: 94.675Å c: 99.183Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.154 0.185
Expression system: Escherichia coli

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