› 3lf6

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163729 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative phosphotransferase system Chains: A, B
Molecule details ›
Chains: A, B
Length: 161 amino acids
Theoretical weight: 18.45 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
Structure domains: Mannitol-specific EII; Chain A

Ligands and Environments

1 bound ligand:
Ligand PO4 3 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 49.211Å b: 81.975Å c: 94.219Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.223 0.279
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

47 review citations

HIV-1 neutralizing antibodies: understanding nature's pathways.
Mascola et al. (2013)
46 more

1 mention without citation

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
Irimia et al. (2017)