› 3lhb

X-ray diffraction
2.7Å resolution

THE 2.7 ANGSTROM CRYSTAL STRUCTURE OF DEOXYGENATED HEMOGLOBIN FROM THE SEA LAMPREY (PETROMYZON MARINUS)

Released:
DOI: 10.2210/pdb3lhb/pdb
PDB entry 3lhb coloured by chain, front view.
PDB entry 3lhb coloured by chain, side view.
PDB entry 3lhb coloured by chain, top view.
Source organism: Petromyzon marinus
Primary publication:
The 2.7 A crystal structure of deoxygenated hemoglobin from the sea lamprey (Petromyzon marinus): structural basis for a lowered oxygen affinity and Bohr effect.
Heaslet HA, Royer WE
Structure 7 517-26 (1999)
PMID: 10378271

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135418 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Globin-5 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 149 amino acids
Theoretical weight: 16.29 KDa
Source organism: Petromyzon marinus
UniProt:
  • Canonical: P02208 (Residues: 2-150; Coverage: 99%)
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 12 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 59.63Å b: 215.16Å c: 75.39Å
α: 90° β: 95.8° γ: 90°
R-values:
R R work R free
0.195 0.195 0.232

Quick links

Citations

5 review citations

Nonvertebrate hemoglobins: functions and molecular adaptations.
Weber et al. (2001)
4 more

1 mention without citation

Simple mechanisms for the evolution of protein complexity.
Pillai et al. (2022)