› 3lhq

X-ray diffraction
1.56Å resolution

DNA-binding transcriptional repressor AcrR from Salmonella typhimurium.

Released:
DOI: 10.2210/pdb3lhq/pdb
PDB entry 3lhq coloured by chain, front view.
PDB entry 3lhq coloured by chain, side view.
PDB entry 3lhq coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Entry authors: Osipiuk J, Mulligan R, Papazisi L, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 220 amino acids
Theoretical weight: 25.21 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7CR15 (Residues: 1-217; Coverage: 100%)
Gene names: STM0477, acrR
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

2 bound ligands:
Ligand PEG 2 x PEG
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 47.18Å b: 75.82Å c: 55.176Å
α: 90° β: 108.67° γ: 90°
R-values:
R R work R free
0.153 0.15 0.199
Expression system: Escherichia coli BL21(DE3)

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