› 3lrb

X-ray diffraction
3.61Å resolution

Structure of E. coli AdiC

Released:
DOI: 10.2210/pdb3lrb/pdb
PDB entry 3lrb coloured by chain, front view.
PDB entry 3lrb coloured by chain, side view.
PDB entry 3lrb coloured by chain, top view.
Source organism: Escherichia coli O157:H7
Primary publication:
Structure and mechanism of an amino acid antiporter.
Gao X, Lu F, Zhou L, Dang S, Sun L, Li X, Wang J, Shi Y
Science 324 1565-8 (2009)
PMID: 19478139

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157971 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arginine/agmatine antiporter Chains: A, B
Molecule details ›
Chains: A, B
Length: 445 amino acids
Theoretical weight: 46.87 KDa
Source organism: Escherichia coli O157:H7
Expression system: Escherichia coli
UniProt:
  • Canonical: P60063 (Residues: 1-445; Coverage: 100%)
Gene names: ECs5097, Z5717, adiC
Sequence domains: Amino acid permease

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 92.81Å b: 108.3Å c: 138.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.296 0.295 0.318
Expression system: Escherichia coli

Quick links

Citations

42 review citations

Biology of human sodium glucose transporters.
Wright et al. (2011)
41 more

14 mentions without citation

Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1.
Singh et al. (2018)
13 more