› 3lui

X-ray diffraction
1.8Å resolution

Crystal structure of the SNX17 PX domain with bound sulphate

Released:
DOI: 10.2210/pdb3lui/pdb
PDB entry 3lui coloured by chain, front view.
PDB entry 3lui coloured by chain, side view.
PDB entry 3lui coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases.
Ghai R, Mobli M, Norwood SJ, Bugarcic A, Teasdale RD, King GF, Collins BM
Proc Natl Acad Sci U S A 108 7763-8 (2011)
PMID: 21512128

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-17 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 115 amino acids
Theoretical weight: 13.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15036 (Residues: 1-112; Coverage: 24%)
Gene names: KIAA0064, SNX17
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 56.893Å b: 66.588Å c: 98.193Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.245
Expression system: Escherichia coli

Quick links

Citations

23 review citations

To degrade or not to degrade: mechanisms and significance of endocytic recycling.
Cullen et al. (2018)
22 more

7 mentions without citation

Translation of the phosphoinositide code by PI effectors.
Kutateladze TG. (2010)
6 more