› 3lul

X-ray diffraction
1.78Å resolution

Crystal structure of Putative 4-amino-4-deoxychorismate lyase. (YP_094631.1) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 at 1.78 A resolution

Released:
DOI: 10.2210/pdb3lul/pdb
PDB entry 3lul coloured by chain, front view.
PDB entry 3lul coloured by chain, side view.
PDB entry 3lul coloured by chain, top view.
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178715 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
4-amino-4-deoxychorismate lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 272 amino acids
Theoretical weight: 31.35 KDa
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5ZXY5 (Residues: 1-271; Coverage: 100%)
Gene name: lpg0595
Sequence domains: Amino-transferase class IV
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EDO 4 x EDO
Ligand PO4 1 x PO4
2 modified residues:
Ligand MSE 8 x MSE
Ligand LLP 2 x LLP

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21212
Unit cell:
a: 85.008Å b: 98.498Å c: 64.599Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.16 0.201
Expression system: Escherichia coli

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