› 3lvs

X-ray diffraction
2.15Å resolution

Crystal structure of farnesyl diphosphate synthase from rhodobacter capsulatus sb1003

Released:
DOI: 10.2210/pdb3lvs/pdb
PDB entry 3lvs coloured by chain, front view.
PDB entry 3lvs coloured by chain, side view.
PDB entry 3lvs coloured by chain, top view.
Source organism: Rhodobacter capsulatus
Primary publication:
Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Wallrapp FH, Pan JJ, Ramamoorthy G, Almonacid DE, Hillerich BS, Seidel R, Patskovsky Y, Babbitt PC, Almo SC, Jacobson MP, Poulter CD
Proc Natl Acad Sci U S A 110 E1196-202 (2013)
PMID: 23493556

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192155 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl diphosphate synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 298 amino acids
Theoretical weight: 31 KDa
Source organism: Rhodobacter capsulatus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9KWR7 (Residues: 1-288; Coverage: 100%)
Sequence domains: Polyprenyl synthetase
Structure domains: Farnesyl Diphosphate Synthase

Ligands and Environments

2 bound ligands:
Ligand PO4 4 x PO4
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 54.456Å b: 89.464Å c: 132.766Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.217 0.25
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks.
Gerlt et al. (2015)
14 more

1 mention without citation

Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Wallrapp et al. (2013)