› 3lwk

X-ray diffraction
1.7Å resolution

Crystal structure of human Beta-crystallin A4 (CRYBA4)

Released:
DOI: 10.2210/pdb3lwk/pdb
PDB entry 3lwk coloured by chain, front view.
PDB entry 3lwk coloured by chain, side view.
PDB entry 3lwk coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Chaikuad A, Shafqat N, Krojer T, Yue WW, Cocking R, Vollmar M, Muniz JRC, Pike ACW, Arrowsmith CH, Weigelt J, Edwards AM, Bountra C, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-crystallin A4 Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53673 (Residues: 8-196; Coverage: 96%)
Gene name: CRYBA4
Sequence domains: Beta/Gamma crystallin
Structure domains: Crystallins

Ligands and Environments

2 bound ligands:
Ligand PO4 1 x PO4
Ligand GOL 5 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: I422
Unit cell:
a: 94.79Å b: 94.79Å c: 90.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.161 0.188
Expression system: Escherichia coli

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