3mbx

X-ray diffraction
1.6Å resolution

Crystal structure of chimeric antibody X836

Released:
Source organism: Mus musculus
Primary publication:
On the domain pairing in chimeric antibodies.
Mol Immunol 47 2422-6 (2010)
PMID: 20554002

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213320 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
X836 LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 220 amino acids
Theoretical weight: 24.52 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins
X836 HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 230 amino acids
Theoretical weight: 24.76 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: I222
Unit cell:
a: 86.93Å b: 99.84Å c: 125.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.21 0.232
Expression system: Homo sapiens