› 3mdx

X-ray diffraction
1.45Å resolution

Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, rhombohedral crystal form

Released:
DOI: 10.2210/pdb3mdx/pdb
PDB entry 3mdx coloured by chain, front view.
PDB entry 3mdx coloured by chain, side view.
PDB entry 3mdx coloured by chain, top view.
Source organism: Brucella abortus 2308
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174207 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxyuridine 5'-triphosphate nucleotidohydrolase Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 18.97 KDa
Source organism: Brucella abortus 2308
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2YRG4 (Residues: 1-157; Coverage: 100%)
Gene names: BAB1_1687, dut
Sequence domains: dUTPase
Structure domains: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: R3
Unit cell:
a: 67.88Å b: 67.88Å c: 95.89Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.151 0.15 0.167
Expression system: Escherichia coli

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