3mo1

X-ray diffraction
1.8Å resolution

Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment

Released:
Source organism: Mus musculus
Entry authors: Nicely NI, Dennison SM, Kelsoe G, Liao H-X, Alam SM, Haynes BF

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213326 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN Chain: A
Molecule details ›
Chain: A
Length: 224 amino acids
Theoretical weight: 24.72 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins
ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN Chain: B
Molecule details ›
Chain: B
Length: 219 amino acids
Theoretical weight: 23.52 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2
Unit cell:
a: 90.365Å b: 60.436Å c: 80.118Å
α: 90° β: 91.22° γ: 90°
R-values:
R R work R free
0.189 0.187 0.221
Expression system: Homo sapiens