› 3muh

X-ray diffraction
3Å resolution

Crystal structure of PG9 light chain

Released:
DOI: 10.2210/pdb3muh/pdb
PDB entry 3muh coloured by chain, front view.
PDB entry 3muh coloured by chain, side view.
PDB entry 3muh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Pejchal R, Walker LM, Stanfield RL, Phogat SK, Koff WC, Poignard P, Burton DR, Wilson IA
Proc Natl Acad Sci U S A 107 11483-8 (2010)
PMID: 20534513

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213328 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Antibody PG9 light chain Chain: L
Molecule details ›
Chain: L
Length: 216 amino acids
Theoretical weight: 22.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P6222
Unit cell:
a: 87.43Å b: 87.43Å c: 198.46Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.248 0.245 0.277
Expression system: Homo sapiens

Quick links

Citations

38 review citations

Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies.
Kwong et al. (2012)
37 more

3 mentions without citation

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Pejchal et al. (2010)
2 more