Function and Biology Details
Reaction catalysed:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
- Flaviviral glycoprotein E, dimerisation domain
- Alphavirus E2 glycoprotein, domain C
- Alphavirus E2 glycoprotein, domain B
- Alphavirus E2 glycoprotein
- Alphavirus E2 glycoprotein, domain A
- Alphavirus E3 spike glycoprotein
- Immunoglobulin E-set
- Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily
2 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
p130 (preferred)
PDBe Complex ID:
PDB-CPX-172869 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Ligands and Environments
Experiments and Validation Details
X-ray source:
SOLEIL BEAMLINE PROXIMA 1
Spacegroup:
P212121
Expression system: Drosophila melanogaster