› 3n50

X-ray diffraction
3.1Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor COE3 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 159 amino acids
Theoretical weight: 17.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H4W6 (Residues: 261-415; Coverage: 26%)
Gene names: COE3, EBF3
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: I23
Unit cell:
a: 229.64Å b: 229.64Å c: 229.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.227
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function.
Boller et al. (2014)
2 more

2 mentions without citation

Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif.
Siponen et al. (2010)
1 more