› 3n5k

X-ray diffraction
2.2Å resolution

Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form

Released:
DOI: 10.2210/pdb3n5k/pdb
PDB entry 3n5k coloured by chain, front view.
PDB entry 3n5k coloured by chain, side view.
PDB entry 3n5k coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt B, Morth JP, Møller JV, Nissen P
J Biol Chem 288 10759-65 (2013)
PMID: 23400778

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 994 amino acids
Theoretical weight: 109.6 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P04191 (Residues: 1-993; Coverage: 99%)
Gene name: ATP2A1
Sequence domains:
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand TG1 2 x TG1
Ligand MG 2 x MG
Ligand ALF 2 x ALF
Ligand K 2 x K
Ligand ACT 4 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 101.93Å b: 109.42Å c: 276.092Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.184 0.216

Quick links

Citations

24 review citations

Emerging Diversity in Lipid-Protein Interactions.
Corradi et al. (2019)
23 more

6 mentions without citation

Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
Bublitz et al. (2013)
5 more