› 3nie

X-ray diffraction
2.3Å resolution

Crystal Structure of PF11_0147

Released:
DOI: 10.2210/pdb3nie/pdb
PDB entry 3nie coloured by chain, front view.
PDB entry 3nie coloured by chain, side view.
PDB entry 3nie coloured by chain, top view.
Source organism: Plasmodium falciparum
Entry authors: Wernimont AK, Hutchinson A, Sullivan H, MacKenzie F, Kozieradzki I, Chau I, Lew J, Senisterra G, Cossar D, Amani M, Artz JD, Bochkarev A, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Hui R, Hills T, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-181603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 429 amino acids
Theoretical weight: 50.15 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7KQK7 (Residues: 95-505; Coverage: 81%)
Gene name: PF3D7_1113900
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ANP 2 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 63.388Å b: 107.355Å c: 70.787Å
α: 90° β: 109.65° γ: 90°
R-values:
R R work R free
0.225 0.223 0.268
Expression system: Escherichia coli

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