› 3njw

X-ray diffraction
0.86Å resolution

First High Resolution Crystal Structure of a Lasso Peptide

Released:
DOI: 10.2210/pdb3njw/pdb
PDB entry 3njw coloured by chain, front view.
PDB entry 3njw coloured by chain, side view.
PDB entry 3njw coloured by chain, top view.
Source organism: Streptomyces sp.
Primary publication:
High-resolution crystal structure of a lasso Peptide.
Nar H, Schmid A, Puder C, Potterat O
ChemMedChem 5 1689-92 (2010)
PMID: 20665759

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bicyclic peptide BI-32169 Chain: A
Molecule details ›
Chain: A
Length: 19 amino acids
Theoretical weight: 2.06 KDa
Source organism: Streptomyces sp.
Expression system: Streptomyces sp.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 19.465Å b: 21.432Å c: 29.523Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.106 not available not available
Expression system: Streptomyces sp.

Quick links

Citations

5 review citations

Lasso peptides: structure, function, biosynthesis, and engineering.
Maksimov et al. (2012)
4 more

7 mentions without citation

Lasso Peptides: Heterologous Production and Potential Medical Application.
Cheng et al. (2020)
6 more