› 3nr3

X-ray diffraction
1.95Å resolution

Crystal Structure of Human Peripheral Myelin Protein 2

Released:
DOI: 10.2210/pdb3nr3/pdb
PDB entry 3nr3 coloured by chain, front view.
PDB entry 3nr3 coloured by chain, side view.
PDB entry 3nr3 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ugochukwu E, Pilka E, Phillips C, Yue WW, Krojer T, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Kavanagh KL, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin P2 protein Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 17.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02689 (Residues: 3-132; Coverage: 99%)
Gene name: PMP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

6 bound ligands:
Ligand PLM 1 x PLM
Ligand SO4 3 x SO4
Ligand GOL 1 x GOL
Ligand CIT 1 x CIT
Ligand EPE 1 x EPE
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41212
Unit cell:
a: 67.19Å b: 67.19Å c: 100.07Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.251
Expression system: Escherichia coli

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