› 3nvg

X-ray diffraction
1.48Å resolution

MIHFGN segment 137-142 from mouse prion

Released:
DOI: 10.2210/pdb3nvg/pdb
PDB entry 3nvg coloured by chain, front view.
PDB entry 3nvg coloured by chain, side view.
PDB entry 3nvg coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Atomic structures suggest determinants of transmission barriers in mammalian prion disease.
Apostol MI, Wiltzius JJ, Sawaya MR, Cascio D, Eisenberg D
Biochemistry 50 2456-63 (2011)
PMID: 21323366

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138275 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 6 amino acids
Theoretical weight: 719 Da
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P04925 (Residues: 137-142; Coverage: 3%)
Gene names: Prn-p, Prnp, Prp

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 27.28Å b: 4.771Å c: 31.476Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.205
Expression system: Not provided

Quick links

Citations

12 review citations

The activities of amyloids from a structural perspective.
Riek et al. (2016)
11 more

6 mentions without citation

Fast and anisotropic flexibility-rigidity index for protein flexibility and fluctuation analysis.
Opron et al. (2014)
5 more