› 3nwo

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed: 
Release of N-terminal proline from a peptide.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106347 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AB hydrolase-1 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 330 amino acids
Theoretical weight: 36.09 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0QVS8 (Residues: 1-309; Coverage: 100%)
Gene name: MSMEG_2681
Sequence domains: alpha/beta hydrolase fold
Structure domains: alpha/beta hydrolase

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand GOL 2 x GOL
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 71.93Å b: 69.92Å c: 55.63Å
α: 90° β: 93.18° γ: 90°
R-values:
R R work R free
0.138 0.136 0.173
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells.
Abu-Remaileh et al. (2015)
5 more

3 mentions without citation

Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA.
Zabrady et al. (2016)
2 more