› 3oa9

X-ray diffraction
2.9Å resolution

Effector domain of influenza A/Duck/Albany/76 NS1

Released:
DOI: 10.2210/pdb3oa9/pdb
PDB entry 3oa9 coloured by chain, front view.
PDB entry 3oa9 coloured by chain, side view.
PDB entry 3oa9 coloured by chain, top view.
Source organism: Influenza A virus (A/duck/Alberta/60/1976(H12N5))
Primary publication:
A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.
Kerry PS, Ayllon J, Taylor MA, Hass C, Lewis A, García-Sastre A, Randall RE, Hale BG, Russell RJ
PLoS One 6 e17946 (2011)
PMID: 21464929

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159565 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 158 amino acids
Theoretical weight: 17.75 KDa
Source organism: Influenza A virus (A/duck/Alberta/60/1976(H12N5))
Expression system: Escherichia coli
UniProt:
  • Canonical: P69270 (Residues: 73-230; Coverage: 69%)
Gene name: NS
Sequence domains: Influenza non-structural protein (NS1)
Structure domains: Influenza virus non-structural protein, effector domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P61
Unit cell:
a: 47.956Å b: 47.956Å c: 231.535Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.225 0.22 0.338
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Induction and evasion of type I interferon responses by influenza viruses.
García-Sastre A. (2011)
9 more

1 mention without citation

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.
Kerry et al. (2011)