› 3odv

X-ray diffraction
0.95Å resolution

X-ray structure of kaliotoxin by racemic protein crystallography

Released:
DOI: 10.2210/pdb3odv/pdb
PDB entry 3odv coloured by chain, front view.
PDB entry 3odv coloured by chain, side view.
PDB entry 3odv coloured by chain, top view.
Source organism: Androctonus mauritanicus mauritanicus
Primary publication:
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.
Pentelute BL, Mandal K, Gates ZP, Sawaya MR, Yeates TO, Kent SB
Chem Commun (Camb) 46 8174-6 (2010)
PMID: 20877851

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150266 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 3.1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 38 amino acids
Theoretical weight: 4.17 KDa
Source organism: Androctonus mauritanicus mauritanicus
Expression system: Not provided
UniProt:
  • Canonical: P24662 (Residues: 1-38; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

2 bound ligands:
Ligand TFA 2 x TFA
Ligand CIT 2 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Unit cell:
a: 25.15Å b: 30.511Å c: 41.097Å
α: 109.39° β: 97.39° γ: 97.09°
R-values:
R R work R free
0.189 0.188 0.203
Expression system: Not provided

Quick links

Citations

7 review citations

Racemic protein crystallography.
Yeates et al. (2012)
6 more

7 mentions without citation

Peptide toxins and small-molecule blockers of BK channels.
Yu et al. (2016)
6 more