› 3ofh

X-ray diffraction
2.01Å resolution

Structured Domain of Mus musculus Mesd

Released:
DOI: 10.2210/pdb3ofh/pdb
PDB entry 3ofh coloured by chain, front view.
PDB entry 3ofh coloured by chain, side view.
PDB entry 3ofh coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Characterization of the Boca/Mesd Maturation Factors for LDL-Receptor-Type beta-Propeller Domains
Collins MN, Hendrickson WA
Structure (2011)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-190175 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LRP chaperone MESD Chains: A, B
Molecule details ›
Chains: A, B
Length: 89 amino acids
Theoretical weight: 10.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9ERE7 (Residues: 98-183; Coverage: 44%)
Gene names: Mesd, Mesdc2
Sequence domains: Chaperone for wingless signalling and trafficking of LDL receptor
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P43
Unit cell:
a: 71.651Å b: 71.651Å c: 37.102Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.15 0.147 0.174
Expression system: Escherichia coli BL21(DE3)

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