› 3ow2

X-ray diffraction
2.7Å resolution

Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit

Released:
DOI: 10.2210/pdb3ow2/pdb
Model geometry
Fit model/data
PDB entry 3ow2 coloured by chain, front view.
PDB entry 3ow2 coloured by chain, side view.
PDB entry 3ow2 coloured by chain, top view.
Source organism: Haloarcula marismortui
Entry author: Kanyo ZF

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 30-mer (preferred)
PDBe Complex ID:
PDB-CPX-300337 (preferred)
Entry contents:
28 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (30 distinct):
Large ribosomal subunit protein uL2 Chain: A
Molecule details ›
Chain: A
Length: 237 amino acids
Theoretical weight: 24.99 KDa
Source organism: Haloarcula marismortui
UniProt:
  • Canonical: P20276 (Residues: 2-238; Coverage: 99%)
Gene names: rpl2, rrnAC1608
Sequence domains:
Structure domains:
Large ribosomal subunit protein uL3 Chain: B
Molecule details ›
Chain: B
Length: 337 amino acids
Theoretical weight: 37.27 KDa
Source organism: Haloarcula marismortui
UniProt:
  • Canonical: P20279 (Residues: 2-338; Coverage: 100%)
Gene names: rpl3, rrnAC1611
Sequence domains: Ribosomal protein L3
Structure domains:
Large ribosomal subunit protein uL4 Chain: C
Large ribosomal subunit protein uL5 Chain: D
Large ribosomal subunit protein uL6 Chain: E
Large ribosomal subunit protein eL8 Chain: F
Large ribosomal subunit protein uL10 Chain: G
50S ribosomal protein L10e Chain: H
Large ribosomal subunit protein uL13 Chain: I
Large ribosomal subunit protein uL14 Chain: J
Large ribosomal subunit protein uL15 Chain: K
Large ribosomal subunit protein eL15 Chain: L
Large ribosomal subunit protein uL18 Chain: M
Large ribosomal subunit protein eL18 Chain: N
Large ribosomal subunit protein eL19 Chain: O
Large ribosomal subunit protein eL21 Chain: P
Large ribosomal subunit protein uL22 Chain: Q
Large ribosomal subunit protein uL23 Chain: R
Large ribosomal subunit protein uL24 Chain: S
Large ribosomal subunit protein eL24 Chain: T
Large ribosomal subunit protein uL29 Chain: U
Large ribosomal subunit protein uL30 Chain: V
Large ribosomal subunit protein eL31 Chain: W
Large ribosomal subunit protein eL32 Chain: X
Large ribosomal subunit protein eL43 Chain: Y
Large ribosomal subunit protein eL37 Chain: Z
Large ribosomal subunit protein eL39 Chain: 1
Large ribosomal subunit protein eL42 Chain: 2
23S ribosomal RNA Chain: 0
5S ribosomal RNA Chain: 9

Ligands and Environments

7 bound ligands:
Ligand MG 61 x MG
Ligand K 1 x K
Ligand NA 26 x NA
Ligand CL 13 x CL
Ligand SR 98 x SR
Ligand EMK 1 x EMK
Ligand CD 4 x CD
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 8-BM
Spacegroup: C2221
Unit cell:
a: 211.853Å b: 298Å c: 574.985Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.222 0.253

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