› 3ox5

X-ray diffraction
2.9Å resolution

Crystal Structure of the calcium sensor calcium-binding protein 1 (CaBP1)

Released:
DOI: 10.2210/pdb3ox5/pdb
PDB entry 3ox5 coloured by chain, front view.
PDB entry 3ox5 coloured by chain, side view.
PDB entry 3ox5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation.
Findeisen F, Minor DL
Structure 18 1617-31 (2010)
PMID: 21134641

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192789 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-binding protein 1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 153 amino acids
Theoretical weight: 17.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NZU7 (Residues: 219-370; Coverage: 41%)
Gene name: CABP1
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 12 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: I23
Unit cell:
a: 206.044Å b: 206.044Å c: 206.044Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.213 0.25
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

Calmodulin regulation (calmodulation) of voltage-gated calcium channels.
Ben-Johny et al. (2014)
12 more

1 mention without citation

Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation.
Findeisen et al. (2010)