3oxr

X-ray diffraction
1.7Å resolution

Crystal Structure of HLA A*02:06 Bound to HBV Core 18-27

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-143051 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5MAG5 (Residues: 25-299; Coverage: 81%)
Gene name: HLA-A
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
External core antigen Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.16 KDa
Source organism: Hepatitis B virus
Expression system: Not provided
UniProt:
  • Canonical: P0C6H2 (Residues: 47-56; Coverage: 5%)
Gene name: C

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 112.4Å b: 79.2Å c: 60.2Å
α: 90° β: 97.2° γ: 90°
R-values:
R R work R free
0.179 0.177 0.214
Expression systems:
  • Escherichia coli
  • Not provided