› 3oyt

X-ray diffraction
1.84Å resolution

1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92

Released:
DOI: 10.2210/pdb3oyt/pdb
Model geometry
Fit model/data
PDB entry 3oyt coloured by chain, front view.
PDB entry 3oyt coloured by chain, side view.
PDB entry 3oyt coloured by chain, top view.
Source organism: Yersinia pestis
Entry authors: Halavaty AS, Wawrzak Z, Onopriyenko O, Peterson S, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO(2) + [acyl-carrier-protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104903 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] synthase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 410 amino acids
Theoretical weight: 44.08 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A2U2H0K6 (Residues: 1-407; Coverage: 100%)
Gene names: YPO2757, fabB, fabC
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1

Ligands and Environments

6 bound ligands:
Ligand K 2 x K
Ligand PO4 3 x PO4
Ligand EDO 4 x EDO
Ligand PEG 8 x PEG
Ligand PGE 1 x PGE
Ligand PG4 2 x PG4
1 modified residue:
Ligand MSE 40 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 21-ID-G, APS BEAMLINE 21-ID-D
Spacegroup: P21212
Unit cell:
a: 109.649Å b: 114.613Å c: 59.157Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.155 0.193
Expression system: Escherichia coli

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