› 3ozq

X-ray diffraction
1.9Å resolution

Crystal structure of Serpin48, which is a highly specific serpin in the insect Tenebrio molitor

Released:
DOI: 10.2210/pdb3ozq/pdb
PDB entry 3ozq coloured by chain, front view.
PDB entry 3ozq coloured by chain, side view.
PDB entry 3ozq coloured by chain, top view.
Source organism: Tenebrio molitor
Primary publication:
Structural and functional characterization of a highly specific serpin in the insect innate immunity.
Park SH, Jiang R, Piao S, Zhang B, Kim EH, Kwon HM, Jin XL, Lee BL, Ha NC
J Biol Chem 286 1567-75 (2011)
PMID: 21047786

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 376 amino acids
Theoretical weight: 42.23 KDa
Source organism: Tenebrio molitor
Expression system: Escherichia coli
UniProt:
  • Canonical: D1MYQ6 (Residues: 17-389; Coverage: 100%)
Gene name: SPN48
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P21
Unit cell:
a: 66.061Å b: 42.561Å c: 66.178Å
α: 90° β: 105.16° γ: 90°
R-values:
R R work R free
0.227 0.221 0.279
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The roles of serpins in mosquito immunology and physiology.
Gulley et al. (2013)
14 other articles

10 mentions without citation

Serpins in arthropod biology.
Meekins et al. (2017)
9 more