3p53

X-ray diffraction
2Å resolution

Structure of fascin

Released:
Source organism: Homo sapiens
Primary publication:
Mechanism of actin filament bundling by fascin.
J Biol Chem 286 30087-96 (2011)
PMID: 21685497

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172542 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fascin Chains: A, B
Molecule details ›
Chains: A, B
Length: 496 amino acids
Theoretical weight: 54.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16658 (Residues: 1-493; Coverage: 100%)
Gene names: FAN1, FSCN1, HSN, SNL
Sequence domains: Fascin domain
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID, null
Spacegroup: C2
Unit cell:
a: 161.693Å b: 71.01Å c: 112.736Å
α: 90° β: 131.23° γ: 90°
R-values:
R R work R free
0.179 0.178 0.22
Expression system: Escherichia coli