› 3phq

X-ray diffraction
2Å resolution

Crystal structure of S64-4 in complex with KDO

Released:
DOI: 10.2210/pdb3phq/pdb
PDB entry 3phq coloured by chain, front view.
PDB entry 3phq coloured by chain, side view.
PDB entry 3phq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.
Evans DW, Müller-Loennies S, Brooks CL, Brade L, Kosma P, Brade H, Evans SV
Glycobiology 21 1049-59 (2011)
PMID: 21543444

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213359 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
S64-4 Fab (IgG1) light chain Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 23.85 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
S64-4 Fab (IgG1) heavy chain Chain: B
Molecule details ›
Chain: B
Length: 222 amino acids
Theoretical weight: 23.79 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand KDO 1 x KDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-002
Spacegroup: P212121
Unit cell:
a: 60.84Å b: 81.15Å c: 94.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.227 0.275

Quick links

Citations

2 review citations

Antibody recognition of carbohydrate epitopes†.
Haji-Ghassemi et al. (2015)
1 more

3 mentions without citation

Blind prediction performance of RosettaAntibody 3.0: grafting, relaxation, kinematic loop modeling, and full CDR optimization.
Weitzner et al. (2014)
2 more