› 3pik

X-ray diffraction
2.3Å resolution

Outer membrane protein CusC

Released:
DOI: 10.2210/pdb3pik/pdb
PDB entry 3pik coloured by chain, front view.
PDB entry 3pik coloured by chain, side view.
PDB entry 3pik coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of Escherichia coli CusC, the outer membrane component of a heavy metal efflux pump.
Kulathila R, Kulathila R, Indic M, van den Berg B
PLoS One 6 e15610 (2011)
PMID: 21249122

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160131 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation efflux system protein CusC Chain: A
Molecule details ›
Chain: A
Length: 446 amino acids
Theoretical weight: 49.39 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P77211 (Residues: 18-457; Coverage: 100%)
Gene names: JW0561, b0572, cusC, ibeB, ylcB
Sequence domains: Outer membrane efflux protein
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand UNL 2 x UNL
Ligand SO4 7 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: R32
Unit cell:
a: 89.03Å b: 89.03Å c: 473.037Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.197 0.243
Expression system: Not provided

Quick links

Citations

15 review citations

The ins and outs of RND efflux pumps in Escherichia coli.
Anes et al. (2015)
14 more

15 mentions without citation

Bacterial multidrug efflux transporters.
Delmar et al. (2014)
14 more