3piq

X-ray diffraction
3.32Å resolution

Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213360 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Human monoclonal antibody 2909 Fab heavy chain Chains: A, C, E, G, H, J
Molecule details ›
Chains: A, C, E, G, H, J
Length: 231 amino acids
Theoretical weight: 24.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Human monoclonal antibody 2909 Fab light chain Chains: B, D, F, I, K, L
Molecule details ›
Chains: B, D, F, I, K, L
Length: 211 amino acids
Theoretical weight: 22.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P3221
Unit cell:
a: 180.373Å b: 180.373Å c: 222.526Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.236 0.299
Expression system: Homo sapiens