› 3pr6

X-ray diffraction
1.8Å resolution

Crystal structure analysis of yeast TRAPP associate protein Tca17

Released:
DOI: 10.2210/pdb3pr6/pdb
PDB entry 3pr6 coloured by chain, front view.
PDB entry 3pr6 coloured by chain, side view.
PDB entry 3pr6 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of the yeast TRAPP-associated protein Tca17.
Wang C, Gohlke U, Roske Y, Heinemann U
FEBS J 281 4195-206 (2014)
PMID: 24961828

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-152399 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TRAPP-associated protein TCA17 Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.35 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P32613 (Residues: 1-152; Coverage: 100%)
Gene names: SYGP-ORF36, TCA17, YEL048C
Sequence domains: Sedlin, N-terminal conserved region
Structure domains: Beta-Lactamase

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand GOL 1 x GOL
2 modified residues:
Ligand MSE 3 x MSE
Ligand CSO 1 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: C2
Unit cell:
a: 57.13Å b: 58.492Å c: 53.969Å
α: 90° β: 92.62° γ: 90°
R-values:
R R work R free
0.185 0.183 0.22
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

TRAPPopathies: An emerging set of disorders linked to variations in the genes encoding transport protein particle (TRAPP)-associated proteins.
Sacher et al. (2019)
1 more

4 mentions without citation

Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1.
Galindo et al. (2021)
3 more