Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
Ubiquitin and RNA-directed RNA polymerase L (preferred)
PDBe Complex ID:
PDB-CPX-216703 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RNA-directed RNA polymerase L
Molecule details ›
Chain: A
Length: 187 amino acids
Theoretical weight: 21.44 KDa
Source organism: Crimean-Congo hemorrhagic fever orthonairovirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: OTU-like cysteine protease
Structure domains: Cathepsin B; Chain A
Length: 187 amino acids
Theoretical weight: 21.44 KDa
Source organism: Crimean-Congo hemorrhagic fever orthonairovirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q6TQR6 (Residues: 1-184; Coverage: 5%)
Sequence domains: OTU-like cysteine protease
Structure domains: Cathepsin B; Chain A
Ubiquitin
Molecule details ›
Chain: B
Length: 75 amino acids
Theoretical weight: 8.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Length: 75 amino acids
Theoretical weight: 8.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P0CG48 (Residues: 609-683; Coverage: 11%)
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
