› 3pxp

X-ray diffraction
2.3Å resolution

Crystal structure of a PAS and DNA binding domain containing protein (Caur_2278) from CHLOROFLEXUS AURANTIACUS J-10-FL at 2.30 A resolution

Released:
DOI: 10.2210/pdb3pxp/pdb
PDB entry 3pxp coloured by chain, front view.
PDB entry 3pxp coloured by chain, side view.
PDB entry 3pxp coloured by chain, top view.
Source organism: Chloroflexus aurantiacus J-10-fl
Primary publication:
Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.
Xu Q, van Wezel GP, Chiu HJ, Jaroszewski L, Klock HE, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA
PLoS One 7 e41359 (2012)
PMID: 22844465

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-109066 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH cro/C1-type domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 292 amino acids
Theoretical weight: 34.5 KDa
Source organism: Chloroflexus aurantiacus J-10-fl
Expression system: Escherichia coli
UniProt:
  • Canonical: A9WGF5 (Residues: 1-291; Coverage: 100%)
Gene name: Caur_2278
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand MYR 3 x MYR
Ligand CL 5 x CL
Ligand EDO 10 x EDO
1 modified residue:
Ligand MSE 33 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2
Unit cell:
a: 228.807Å b: 83.568Å c: 54.52Å
α: 90° β: 103.12° γ: 90°
R-values:
R R work R free
0.169 0.168 0.206
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Molecular regulation of antibiotic biosynthesis in streptomyces.
Liu et al. (2013)
3 more

3 mentions without citation

PAS domains in bacterial signal transduction.
Stuffle et al. (2021)
2 more