3q0k

X-ray diffraction
2.6Å resolution

Crystal structure of Human PACSIN 2 F-BAR

Released:
Source organism: Homo sapiens
Entry authors: Bai X, Meng G, Zheng X

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-193992 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C and casein kinase substrate in neurons protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 289 amino acids
Theoretical weight: 34.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UNF0 (Residues: 16-304; Coverage: 60%)
Gene name: PACSIN2
Sequence domains: Fes/CIP4, and EFC/F-BAR homology domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P21
Unit cell:
a: 31.562Å b: 353.588Å c: 86.045Å
α: 90° β: 90.02° γ: 90°
R-values:
R R work R free
0.22 0.201 0.292
Expression system: Escherichia coli BL21(DE3)