3q73

X-ray diffraction
2.3Å resolution

Cryptococcus neoformans protein farnesyltransferase, apo enzyme

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-241332 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Farnesyltransferase, alpha subunit Chain: A
Molecule details ›
Chain: A
Length: 349 amino acids
Theoretical weight: 40.91 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli
Structure domains: Protein prenylyltransferase
Farnesyltransferase, beta subunit Chain: B
Molecule details ›
Chain: B
Length: 520 amino acids
Theoretical weight: 56.81 KDa
Source organism: Cryptococcus neoformans var. grubii H99
Expression system: Escherichia coli
Structure domains: Glycosyltransferase

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC, FRU
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P43212
Unit cell:
a: 144.041Å b: 144.041Å c: 130.444Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.193 0.22
Expression system: Escherichia coli