› 3q7k

X-ray diffraction
2.8Å resolution

Formate Channel FocA from Salmonella typhimurium

Released:
DOI: 10.2210/pdb3q7k/pdb
PDB entry 3q7k coloured by chain, front view.
PDB entry 3q7k coloured by chain, side view.
PDB entry 3q7k coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhi str. CT18
Primary publication:
pH-dependent gating in a FocA formate channel.
Lü W, Du J, Wacker T, Gerbig-Smentek E, Andrade SL, Einsle O
Science 332 352-4 (2011)
PMID: 21493860

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181421 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Formate transporter Chains: A, B, C, D, E, G, H, I, J, K
Molecule details ›
Chains: A, B, C, D, E, G, H, I, J, K
Length: 293 amino acids
Theoretical weight: 32.06 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhi str. CT18
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7CQU0 (Residues: 1-285; Coverage: 100%)
Gene names: STM0974, focA
Sequence domains: Formate/nitrite transporter
Structure domains: Glycerol uptake facilitator protein.

Ligands and Environments

1 bound ligand:
Ligand FMT 13 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 105.951Å b: 205.723Å c: 106.046Å
α: 90° β: 115.49° γ: 90°
R-values:
R R work R free
0.22 0.219 0.254
Expression system: Escherichia coli

Quick links

Citations

7 review citations

How to make a living from anaerobic ammonium oxidation.
Kartal et al. (2013)
6 more

10 mentions without citation

Ion selectivity and gating mechanisms of FNT channels.
Waight et al. (2013)
9 more