› 3q88

X-ray diffraction
1.7Å resolution

Glucose-6-phosphate isomerase from Francisella tularensis complexed with ribose 1,5-bisphosphate.

Released:
DOI: 10.2210/pdb3q88/pdb
PDB entry 3q88 coloured by chain, front view.
PDB entry 3q88 coloured by chain, side view.
PDB entry 3q88 coloured by chain, top view.
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Entry authors: Osipiuk J, Maltseva N, Hasseman J, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
Alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177662 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 543 amino acids
Theoretical weight: 61.47 KDa
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5NFC4 (Residues: 1-540; Coverage: 100%)
Gene names: FTT_1315c, pgi
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand RI2 1 x RI2
Ligand MES 2 x MES
Ligand PO4 1 x PO4
Ligand IPA 1 x IPA
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3221
Unit cell:
a: 114.465Å b: 114.465Å c: 84.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.148 0.146 0.174
Expression system: Escherichia coli

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