› 3q90

X-ray diffraction
1.7Å resolution

Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1

Released:
DOI: 10.2210/pdb3q90/pdb
PDB entry 3q90 coloured by chain, front view.
PDB entry 3q90 coloured by chain, side view.
PDB entry 3q90 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Welin M, Tresaugues L, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Ekblad T, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson I, Karlberg T, Kol S, Kotenyova T, Kouznetsova E, Moche M, Nyman T, Persson C, Schuler H, Schutz P, Siponen MI, Thorsell AG, Van Der Berg S, Wahlberg E, Weigelt J, Nordlund P, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras GTPase-activating protein-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 15.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13283 (Residues: 1-139; Coverage: 30%)
Gene names: G3BP, G3BP1
Sequence domains: Nuclear transport factor 2 (NTF2) domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P212121
Unit cell:
a: 42.85Å b: 71.41Å c: 88.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.214 0.238
Expression system: Escherichia coli BL21(DE3)

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