› 3qdw

X-ray diffraction
1.9Å resolution

Structure of the hexagonal form of the Boletus edulis lectin in complex with N-acetyl glucosamine and N-acetyl galactosamine

Released:
DOI: 10.2210/pdb3qdw/pdb
PDB entry 3qdw coloured by chain, front view.
PDB entry 3qdw coloured by chain, side view.
PDB entry 3qdw coloured by chain, top view.
Source organism: Boletus edulis
Primary publication:
Structure of a lectin with antitumoral properties in king bolete (Boletus edulis) mushrooms.
Bovi M, Carrizo ME, Capaldi S, Perduca M, Chiarelli LR, Galliano M, Monaco HL
Glycobiology 21 1000-9 (2011)
PMID: 21303815

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123435 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Boletus edulis lectin Chains: A, B
Molecule details ›
Chains: A, B
Length: 143 amino acids
Theoretical weight: 15.85 KDa
Source organism: Boletus edulis
UniProt:
  • Canonical: F2Z266 (Residues: 2-143; Coverage: 99%)
Sequence domains: Fungal fruit body lectin
Structure domains: Cytolysin/lectin

Ligands and Environments

2 bound ligands:
Ligand A2G 2 x A2G
Ligand NDG 2 x NDG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: P6122
Unit cell:
a: 123.818Å b: 123.818Å c: 104.322Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.196

Quick links

Citations

5 review citations

Fungal lectins: structure, function and potential applications.
Varrot et al. (2013)
4 more

1 mention without citation

Mushroom lectins: specificity, structure and bioactivity relevant to human disease.
Hassan et al. (2015)