› 3qe3

X-ray diffraction
1.9Å resolution

Sheep liver sorbitol dehydrogenase

Released:
DOI: 10.2210/pdb3qe3/pdb
PDB entry 3qe3 coloured by chain, front view.
PDB entry 3qe3 coloured by chain, side view.
PDB entry 3qe3 coloured by chain, top view.
Source organism: Ovis aries
Primary publication:
X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase.
Yennawar H, Møller M, Gillilan R, Yennawar N
Acta Crystallogr D Biol Crystallogr 67 440-6 (2011)
PMID: 21543846

Function and Biology Details

Reactions catalysed: 
L-iditol + NAD(+) = L-sorbose + NADH
Xylitol + NAD(+) = D-xylulose + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139790 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorbitol dehydrogenase Chain: A
Molecule details ›
Chain: A
Length: 355 amino acids
Theoretical weight: 38.01 KDa
Source organism: Ovis aries
Expression system: Escherichia coli
UniProt:
  • Canonical: P07846 (Residues: 1-51, 52-354; Coverage: 100%)
Gene name: SORD
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand ZN 1 x ZN
Ligand GOL 1 x GOL
Ligand ACY 3 x ACY
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: I222
Unit cell:
a: 67.749Å b: 85.881Å c: 119.888Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.234
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

New insights into the evolutionary history of plant sorbitol dehydrogenase.
Jia et al. (2015)
1 more

6 mentions without citation

An active murine transposon family pair: retrotransposition of "master" MusD copies and ETn trans-mobilization.
Ribet et al. (2004)
5 more