› 3qe7

X-ray diffraction
2.78Å resolution

Crystal Structure of Uracil Transporter--UraA

Released:
DOI: 10.2210/pdb3qe7/pdb
PDB entry 3qe7 coloured by chain, front view.
PDB entry 3qe7 coloured by chain, side view.
PDB entry 3qe7 coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Structure and mechanism of the uracil transporter UraA.
Lu F, Li S, Jiang Y, Jiang J, Fan H, Lu G, Deng D, Dang S, Zhang X, Wang J, Yan N
Nature 472 243-6 (2011)
PMID: 21423164

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-142845 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uracil permease Chain: A
Molecule details ›
Chain: A
Length: 429 amino acids
Theoretical weight: 45.09 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AGM7 (Residues: 1-429; Coverage: 100%)
Gene names: JW2482, b2497, uraA
Sequence domains: Permease family

Ligands and Environments

2 bound ligands:
Ligand URA 1 x URA
Ligand BNG 1 x BNG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P6422
Unit cell:
a: 96.76Å b: 96.76Å c: 251.95Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.248 0.304
Expression system: Escherichia coli

Quick links

Citations

25 review citations

The ABCs of membrane transporters in health and disease (SLC series): introduction.
Hediger et al. (2013)
24 more

17 mentions without citation

Influences of membrane mimetic environments on membrane protein structures.
Zhou et al. (2013)
16 more