› 3qrn

X-ray diffraction
1.1Å resolution

X-ray crystal structure of the ruthenium complex [Ru(tap)2(dppz)]2+ bound to d(TCGGCGCCGA)at high resolution

Released:
DOI: 10.2210/pdb3qrn/pdb
PDB entry 3qrn coloured by chain, front view.
PDB entry 3qrn coloured by chain, side view.
PDB entry 3qrn coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand.
Hall JP, O'Sullivan K, Naseer A, Smith JA, Kelly JM, Cardin CJ
Proc Natl Acad Sci U S A 108 17610-4 (2011)
PMID: 21969542

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116783 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3' Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand RKL 1 x RKL
Ligand BA 1 x BA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P43212
Unit cell:
a: 42.32Å b: 42.32Å c: 39.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.108 0.107 0.124
Expression system: Not provided

Quick links

Citations

5 review citations

The path for metal complexes to a DNA target.
Komor et al. (2013)
4 more

3 mentions without citation

A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding.
Satange et al. (2018)
2 more