Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Translational (tr)-type GTP-binding domain
- Translation initiation factor 2, alpha subunit, C-terminal
- Initiation factor eIF2 gamma, C-terminal
- P-loop containing nucleoside triphosphate hydrolase
- Translation initiation factor 2, gamma subunit
- Translation initiation factor 2, alpha subunit
- Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
- Translation elongation factor EFTu-like, domain 2
5 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Translation initiation factor 2 and RNA (preferred)
PDBe Complex ID:
PDB-CPX-189062 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (3 distinct):
Translation initiation factor 2 subunit gamma
Molecule details ›
Chain: A
Length: 415 amino acids
Theoretical weight: 45.85 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 415 amino acids
Theoretical weight: 45.85 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q980A5 (Residues: 1-415; Coverage: 100%)
Sequence domains:
Structure domains:
Translation initiation factor 2 subunit alpha
Molecule details ›
Chain: B
Length: 89 amino acids
Theoretical weight: 9.89 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
Sequence domains: Eukaryotic translation initiation factor 2 alpha subunit
Structure domains: EIF_2_alpha
Length: 89 amino acids
Theoretical weight: 9.89 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
- Canonical: Q97Z79 (Residues: 176-264; Coverage: 34%)
Sequence domains: Eukaryotic translation initiation factor 2 alpha subunit
Structure domains: EIF_2_alpha
