› 3r05

X-ray diffraction
2.95Å resolution

Structure of neurexin 1 alpha (domains LNS1-LNS6), with splice insert SS3

Released:
DOI: 10.2210/pdb3r05/pdb
PDB entry 3r05 coloured by chain, front view.
PDB entry 3r05 coloured by chain, side view.
PDB entry 3r05 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The structure of neurexin 1α reveals features promoting a role as synaptic organizer.
Chen F, Venugopal V, Murray B, Rudenko G
Structure 19 779-89 (2011)
PMID: 21620716

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173308 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Neurexin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1254 amino acids
Theoretical weight: 138.51 KDa
Source organism: Bos taurus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q28146 (Residues: 31-1355; Coverage: 83%)
Gene name: NRXN1
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P1
Unit cell:
a: 61.03Å b: 114.574Å c: 160.129Å
α: 89.6° β: 89.98° γ: 87.96°
R-values:
R R work R free
0.21 0.208 0.235
Expression system: Spodoptera frugiperda

Quick links

Citations

9 review citations

The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses.
Krueger et al. (2012)
8 more

9 mentions without citation

Neurexins.
Reissner et al. (2013)
8 more