› 3r12

X-ray diffraction
1.75Å resolution

Crystal structure of a Deoxyribose-phosphate aldolase (TM_1559) from THERMOTOGA MARITIMA at 1.75 A resolution

Released:
DOI: 10.2210/pdb3r12/pdb
PDB entry 3r12 coloured by chain, front view.
PDB entry 3r12 coloured by chain, side view.
PDB entry 3r12 coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194825 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxyribose-phosphate aldolase Chains: A, B
Molecule details ›
Chains: A, B
Length: 260 amino acids
Theoretical weight: 29.16 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X1P5 (Residues: 1-248; Coverage: 100%)
Gene names: TM_1559, deoC
Sequence domains: DeoC/LacD family aldolase
Structure domains: Aldolase class I

Ligands and Environments

3 bound ligands:
Ligand CIT 2 x CIT
Ligand PGO 1 x PGO
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21
Unit cell:
a: 53.812Å b: 51.818Å c: 84.735Å
α: 90° β: 95.23° γ: 90°
R-values:
R R work R free
0.155 0.153 0.192
Expression system: Escherichia coli

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